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Transforming Treatment for Autoimmune Diseases
Read about the promise of cellular therapies and our work in Breakthrough
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We are excited to host an outstanding panel of speakers on precision cellular immunotherapies and CAR-Tregs at The American College of Rheumatology Symposium at FOCIS 2023!
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CATCR-T cell therapy may aid in antiphospholipid syndrome through selective B-cell depletion
Upcoming T-cell therapies may treat antiphospholipid syndrome and other autoimmune diseases without compromising a patient’s defenses against infection.
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Learn about our precision immunotherapy work at #ACR22
We introduce CATCR-T cells, a novel engineered T cell receptor technology to selectively target autoreactive B cells that drive autoimmune diseases (Plenary Session III, November 14, 2022).
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Mutant Gene-Targeted Immunotherapy Approach Developed
A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.
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Cancer Immunotherapy Approach Targets Common Genetic Alteration
Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers.
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Increased Survival in Patients with Pneumonia Taking Alpha-1 Blockers at Baseline
The benefit of alpha blockers may extend to other respiratory infection. Read more in eLife.
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Alpha-1 Blockers are Associated with Increased Survival in COVID-19
Retrospective data from the United States Department of Veterans Affairs suggests benefit of inhibiting catecholamine-mediated cytokine dysregulation to prevent severe COVID-19
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Storm Cells
Researchers at Johns Hopkins are racing to understand the connection between SARS-CoV-2 and a deadly immune system malfunction called a cytokine storm.
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Researchers Urge Clinical Trial to Prevent Lethal Complication of COVID-19
Read more on Johns Hopkins News
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Aggregatibacter Actinomycetemcomitans May Be a Trigger for Rheumatoid Arthritis
Read our interview on Healio Rheumatology
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How a Periodontal Infection Might Trigger RA
A pathogen linked to periodontal disease might trigger production of autoantigens that set off and sustain inflammatory immune responses in the joints in rheumatoid arthritis (RA).
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Linking Rheumatoid Arthritis and Gum Disease: Researchers Find Common Bacterium
Researchers from Johns Hopkins Medicine have narrowed down the link between chronic gum disease and rheumatoid arthritis, identifying the common bacterium at play in both conditions.